Blar i forfatter "Lien, Sigbjørn"

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    • The genome sequence of Atlantic cod reveals a unique immune system 

      Star, Bastiaan; Nederbragt, Alexander Johan; Jentoft, Sissel; Grimholt, Unni; Malmstrøm, Martin; Gregers, Tone Fredsvik; Rounge, Trine Ballestad; Paulsen, Jonas; Solbakken, Monica Hongrø; Sharma, Animesh; Wetten, Ola Frang; Lanzén, Anders; Winer, Roger; Knight, James; Vogel, Jan-Hinnerk; Aken, Bronwen; Andersen, Øivind; Lagesen, Karin; Tooming-Klunderud, Ave; Edvardsen, Rolf; Kirubakaran, G. Tina; Espelund, Mari; Nepal, Chirag; Previti, A. Christopher; Karlsen, Bård Ove; Moum, Truls; Skage, Morten; Berg, Paul Ragnar; Gjøen, Tor; Kuhl, Heiner; Thorsen, Jim; Malde, Ketil; Reinhardt, Richard; Du, Lei; Johansen, Steinar Daae; Searle, Steve; Lien, Sigbjørn; Nilsen, Frank; Jonassen, Inge; Omholt, Stig W; Stenseth, Nils Christian; Jakobsen, Kjetill Sigurd (Journal article; Tidsskriftartikkel; Peer reviewed, 2011-08-10)
      Atlantic cod (Gadus morhua) is a large, cold-adapted teleost that sustains long-standing commercial fisheries and incipient aquaculture1, 2. Here we present the genome sequence of Atlantic cod, showing evidence for complex thermal adaptations in its haemoglobin gene cluster and an unusual immune architecture compared to other sequenced vertebrates. The genome assembly was obtained exclusively by 454 ...

    • Genome-Wide Reconstruction of Rediploidization Following Autopolyploidization across One Hundred Million Years of Salmonid Evolution 

      Gundappa, Manu Kumar; To, Thu-Hien; Grønvold, Lars; Martin, Samuel A. M.; Lien, Sigbjørn; Geist, Jürgen; Hazlerigg, David; Sandve, Simen Rød; Macqueen, Daniel J. (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-10-28)
      The long-term evolutionary impacts of whole-genome duplication (WGD) are strongly influenced by the ensuing rediploidization process. Following autopolyploidization, rediploidization involves a transition from tetraploid to diploid meiotic pairing, allowing duplicated genes (ohnologs) to diverge genetically and functionally. Our understanding of autopolyploid rediploidization has been informed ...

    • Hierarchical genetic structure in an evolving species complex: Insights from genome wide ddRAD data in Sebastes mentella 

      Saha, Atal; Kent, Matthew Peter; Hauser, Lorenz; Drinan, Daniel P.; Nielsen, Einar E.; Westgaard, Jon-Ivar; Lien, Sigbjørn; Johansen, Torild (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-05-27)
      The diverse biology and ecology of marine organisms may lead to complex patterns of intraspecific diversity for both neutral and adaptive genetic variation. Sebastes mentella displays a particular life-history as livebearers, for which existence of multiple ecotypes has been suspected to complicate the genetic population structure of the species. Double digest restriction-site associated DNA was ...

    • Identification and characterisation of novel SNP markers in Atlantic cod: evidence for directional selection 

      Fevolden, Svein-Erik; Moen, Thomas; Hayes, Ben; Nilsen, Frank; Delghandi, Madjid; Fjalestad, Kjersti; Berg, Paul R.; Lien, Sigbjørn (Journal article; Tidsskriftartikkel; Peer reviewed, 2008-02-26)
      Background: The Atlantic cod (Gadus morhua) is a groundfish of great economic value in fisheries and an emerging species in aquaculture. Genetic markers are needed to identify wild stocks in order to ensure sustainable management, and for marker-assisted selection and pedigree determination in aquaculture. Here, we report on the development and evaluation of a large number of Single Nucleotide ...